These, coupled with real-time imaging of specific stem cells engrafting in their niche, provide new opportunities for understanding and manipulating the processes crucial for stem cell transplantation. His contributions have modified thinking in the field and given direction for interventions to improve transplantation. Leonard I. Zon, MD, of Children’s Hospital and Dana-Farber Malignancy Institute, Howard Hughes Medical Institute, Harvard Stem Cell Institute, Harvard Medical College, Boston, MA, will become recognized with the E.Jo Ivey Boufford and seven other health plan and evaluation specialists from NYAM may also present abstracts on a range of health policy issues at the meeting.. Adult leukaemias: prognostic classification and treatment Improved knowledge of the molecular basis of leukaemias in adults offers led to major changes in the diagnosis, treatment and classification of the diseases. Leukaemia in adults isn’t an individual disease but a number of biologically and clinically distinctive syndromes. Advances in the understanding of the molecular basis of leukaemia offers improved prognostic classification and radically changed therapy .