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Within the allergen-problem group, the raises in both of these variables after the problem were significant . The median number of endobronchial mucosal eosinophils increased after the allergen problem also, from 3.25 cells per square millimeter to 11.00 cells per square millimeter . No significant adjustments were evident in the other organizations with respect to tissue eosinophils. There were no significant differences between groups in any other bronchoalveolar-lavage fluid or tissue cellular types examined . Epithelial Repair and Structural Remodeling Before the problems, there were no significant differences among the four groups regarding the histochemical measurements obtained .01) .