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More importantly, their sufferers experienced a progressive improvement in all clinical parameters which are still persisting a yr after treatment. All individuals experienced improvement in their walking exams, ankle brachial pressure index, oxygen pressure, angiography and quality of life, Lasala stated. Coronary Ischemia Coronary Ischemia is certainly intractable angina due to serious coronary artery disease that may seriously decrease blood flow to the center. Drs. Lasala and Minguell finished the Phase I protocol this past year and is currently conducting Phase II involving 60 individuals.